Pythia Biosciences and CyberomiX Partner to Streamline Japan's Single-Cell Research, from Data Generation to Analysis

SAN DIEGO, CA, UNITED STATES, January 26, 2026 –– Pythia Biosciences and CyberomiX Inc. today announced a strategic collaboration aimed at supporting the rapidly growing demand for single-cell omics research in Japan. Through this partnership, Pythia will support CyberomiX customers with advanced, interactive analysis of single-cell data using its flagship platform, the C-DIAM Multi-Omics Studio.

Although single-cell and spatial omics data have been widely adopted in recent years, the datasets themselves are becoming increasingly large and complex. Few existing tools help with this, but users must have advanced coding skills; this has hindered researchers from fully utilizing the data. CyberomiX, coined from “Cyber” and “Omics”, is a Japanese biotech company specializing in advanced genomic analysis that offers full-service solutions from sample preparation to data interpretation with solid experience assisting multi-omics research in both academia and industry. Through this collaboration, customers of CyberomiX will now have the opportunity to license C-DIAM and self-discover single-cell downstream analysis more easily.

Developed by Pythia BioSciences, C-DIAM Multi-omics Studio is a SaaS platform (no installation required) that supports interactive analysis and integration across multiple omics layers, prominently single-cell RNA-seq and spatial transcriptomics, alongside bulk RNA-seq, proteomics and metabolomics. Key functionalities include cell type prediction, differential expression (DE) analysis, sub-clustering, marker gene identification, pathway enrichment, and workflows for target and biomarker discovery. This also includes integration with public or internally built pipelines and tools (like R Shiny data visualization applications).

Limitations in omics research may also arise from the lack of sharing features, or from insufficient support for comparing insights with researchers’ own experiments. C-DIAM platform solves this problem by allowing users to merge insights across studies, including public and in-house data. Results can also be shared easily with convenient collaboration options such as URLs or shared project notebooks. The platform features an intuitive graphical interface, so scientists with no coding background can also navigate with ease. For users who prefer programmatic workflows, C-DIAM also supports advanced exploration through APIs and access to Pythia’s large curated Pythiomics database spanning multiple therapeutic areas. In the latest update in 2025, C-DIAM extends its features further by allowing users to explore gene expression patterns and identify DE genes across the entire database of Pythiomics, which includes approximately 137 million cells. For spatial transcriptomics, it now also provides new features, including lasso selection on Xenium images.

“We provide bioinformatics expert–driven data analysis services. At the same time, we see strong demand from customers who want to perform analyses independently without relying on command-line operations. In response to this need, we have been exploring no-code software solutions and found C-DIAM Multi-Omics Studio, developed by Pythia, to be highly suitable.”

Akira Watanabe, Ph.D., CEO of CyberomiX Inc.

This collaboration marks Pythia’s third Japanese partnership in 2025. “We are proud to be part of the discovery here and look forward to witnessing upcoming breakthroughs in single-cell analysis, starting from this partnership”, commented Tristan Gill, CEO of Pythia Biosciences. Akira Watanabe, Ph.D., CEO of CyberomiX Inc, added: “We provide bioinformatics expert–driven data analysis services. At the same time, we see strong demand from customers who want to perform analyses independently without relying on command-line operations. In response to this need, we have been exploring no-code software solutions and found C-DIAM Multi-Omics Studio, developed by Pythia, to be highly suitable. We are pleased to make this software available to our customers.”

For more information about the collaboration, please contact Pythia Biosciences at www.pythiabio.com or CyberomiX at: https://cyberomix.co.jp/.

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About Pythia Biosciences

Pythia Biosciences was founded with an aim to help scientists tackle the top challenges in multi-omics data analysis by developing cutting-edge software platforms combined with omics data curation and comprehensive bioinformatics services. The company's flagship platform, the C-DIAM Multi-Omics Studio, empowers biomedical researchers to analyze and integrate diverse omics datasets with modern visualizations and interactive analytics, facilitating a bigger picture about biology.

About CyberomiX

CyberomiX is a genomics startup offering bulk, single-cell, and spatial RNA-seq solutions from sample to insight. Inspired by Nishijin weaving, an art form shaped over centuries through the fusion of Kyoto’s tradition and global innovation, we integrate diverse technologies to drive life science forward. Beyond conventional academic collaboration, our mission is to walk alongside scientists at every step of their analysis journey - engaging in deep discussions, integrating knowledge, and working together to generate breakthrough scientific insight rather than simply delivering results.

*Nishijin: Kyoto’s rich tradition of textile weaving